2011年4月14日星期四

Limbs grow back the now possible in some mammals

Limb-regrowth

On the day than perhaps humans and mammals could produce limbs, a breakthrough soon approaching as a scientist in the area.

The first phase of limb regeneration observed in some amphibians, has echinoderms and many plants have been replicated in mice for the first time, according to new research in the journal ACS chemical biology featured.

The project is the first time scientists these early stages of limb regeneration in mammals have been replicated.

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Essentially the process is something differentiation similar to stem cells. Another step is instead to turn non-specialized cells in specialized cells such as heart and skin cells.

Turn in unspecialized cells in a process called "Dedifferentiation" specialized cells like in bone muscle and then change into a different type of specialized cells other than what they started.

In the experiment scientists is a combination of chemicals on skeletal muscle in mice tissues in the hopes of dedifferentiation create applied. This contain linked specifically, known as "small molecules" and changes to the sponsors or a series of DNA that controls a specific gene.

After applying the treatment on the skeletal muscle cells, could the researchers to coax cells in bone and fat cells, a large in the early stages of limb regeneration role to change.

With more research, it is plausible that the technique could benefit, humans and mammals, the limbs lost in accidents.

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But in the short-term, regenerating limbs is not all that be won. Understand, such as cells are multipotent, researchers can new treatments for patients Wunden--create in connection with limbs or otherwise.

For salamander limbs grow back about 40 days after a limb was interrupted. The technology also takes several days, but seems most effective when applied in the first minutes after injury, say the researchers.

Photo by Sarah_Jones/Flickr.com






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